|
KMID : 1134819980270010157
|
|
Journal of the Korean Society of Food Science and Nutrition
1998 Volume.27 No. 1 p.157 ~ p.162
|
|
|
Antimutagenicity and Cytotoxicity of Artemisia iwayomogi Kitamura Extracts
|
|
Ham Seung-Shi
Chung Cha-Kwon
Lee Jae-Hoon
Chio Geun-Pyo
Jung Seung-Won
Kim Eun-Jeong
|
|
|
Abstract
|
|
|
|
The antimutagenic activity of three kinds of extract such as fresh juice, ethanol extract and water extract of Artemisia iwayomogi against 3-amino-l,4-dimethyl-5H-pyrido[4,3-b]indol(Trp-P-1) and N-methyl-N’-nitro-N-nitrosoguanidine(MNNG) was demonstrated with the Salmonella typhirnurium assay. The numbers of revertants per plate decreased significantly when these extracts(0.5㎍/plate) added to the assay system using S. typhimurium TA100. These extracts also showed prominant cytotoxic activity against four different kinds of human cancer cell such as human lung cancer cell(A549), breast cancer cell(MCF7), fibrosacoma cell(HT1080) and gastric cancer cell(KATOⅢ), respectively.
|
|
|
KEYWORD
|
|
|
antimutagenicity, Artemisia iwayomogi, cytotoxicity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|